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A Functional Nuclear Epidermal Growth Factor Receptor, Src and Stat3 Heteromeric Complex in Pancreatic Cancer Cells

Evidence is presented for the nuclear presence of a functional heteromeric complex of epidermal growth factor (EGFR), Src and the Signal Transducer and Activator of Transcription (Stat)3 proteins in pancreatic cancer cells. Stat3 remains nuclear and associated with Src or EGFR, respectively, upon th...

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Detalles Bibliográficos
Autores principales: Jaganathan, Soumya, Yue, Peibin, Paladino, David C., Bogdanovic, Jelena, Huo, Qun, Turkson, James
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088706/
https://www.ncbi.nlm.nih.gov/pubmed/21573184
http://dx.doi.org/10.1371/journal.pone.0019605