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A Latent Pro-Survival Function for the Mir-290-295 Cluster in Mouse Embryonic Stem Cells

MicroRNAs (miRNAs) post-transcriptionally regulate the expression of thousands of distinct mRNAs. While some regulatory interactions help to maintain basal cellular functions, others are likely relevant in more specific settings, such as response to stress. Here we describe such a role for the mir-2...

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Detalles Bibliográficos
Autores principales: Zheng, Grace X. Y., Ravi, Arvind, Calabrese, J. Mauro, Medeiros, Lea A., Kirak, Oktay, Dennis, Lucas M., Jaenisch, Rudolf, Burge, Christopher B., Sharp, Phillip A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088722/
https://www.ncbi.nlm.nih.gov/pubmed/21573140
http://dx.doi.org/10.1371/journal.pgen.1002054