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A Latent Pro-Survival Function for the Mir-290-295 Cluster in Mouse Embryonic Stem Cells
MicroRNAs (miRNAs) post-transcriptionally regulate the expression of thousands of distinct mRNAs. While some regulatory interactions help to maintain basal cellular functions, others are likely relevant in more specific settings, such as response to stress. Here we describe such a role for the mir-2...
Autores principales: | Zheng, Grace X. Y., Ravi, Arvind, Calabrese, J. Mauro, Medeiros, Lea A., Kirak, Oktay, Dennis, Lucas M., Jaenisch, Rudolf, Burge, Christopher B., Sharp, Phillip A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088722/ https://www.ncbi.nlm.nih.gov/pubmed/21573140 http://dx.doi.org/10.1371/journal.pgen.1002054 |
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