DISC1-dependent switch from progenitor proliferation to migration in the developing cortex

Regulatory mechanisms governing the sequence from progenitor cell proliferation to neuronal migration during corticogenesis are poorly understood1–10. Here we report that phosphorylation of DISC1, a major susceptibility factor for several mental disorders, acts as a molecular switch from maintaining...

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Detalles Bibliográficos
Autores principales: Ishizuka, Koko, Kamiya, Atsushi, Oh, Edwin C., Kanki, Hiroaki, Seshadri, Saurav, Robinson, Jon F., Murdoch, Hannah, Dunlop, Allan J., Kubo, Ken-ichiro, Furukori, Keiko, Huang, Beverly, Zeledon, Mariela, Hayashi-Takagi, Akiko, Okano, Hideyuki, Nakajima, Kazunori, Houslay, Miles D., Katsanis, Nicholas, Sawa, Akira
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088774/
https://www.ncbi.nlm.nih.gov/pubmed/21471969
http://dx.doi.org/10.1038/nature09859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088774/
https://www.ncbi.nlm.nih.gov/pubmed/21471969
http://dx.doi.org/10.1038/nature09859

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