Structural insights into the cTAR DNA recognition by the HIV-1 nucleocapsid protein: role of sugar deoxyriboses in the binding polarity of NC

An essential step of the reverse transcription of the HIV-1 genome is the first strand transfer that requires the annealing of the TAR RNA hairpin to the cTAR DNA hairpin. HIV-1 nucleocapsid protein (NC) plays a crucial role by facilitating annealing of the complementary hairpins. Using nuclear magn...

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Detalles Bibliográficos
Autores principales: Bazzi, Ali, Zargarian, Loussiné, Chaminade, Françoise, Boudier, Christian, De Rocquigny, Hughes, René, Brigitte, Mély, Yves, Fossé, Philippe, Mauffret, Olivier
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089453/
https://www.ncbi.nlm.nih.gov/pubmed/21227929
http://dx.doi.org/10.1093/nar/gkq1290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089453/
https://www.ncbi.nlm.nih.gov/pubmed/21227929
http://dx.doi.org/10.1093/nar/gkq1290

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