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Molecular determinants of origin discrimination by Orc1 initiators in archaea

Unlike bacteria, many eukaryotes initiate DNA replication from genomic sites that lack apparent sequence conservation. These loci are identified and bound by the origin recognition complex (ORC), and subsequently activated by a cascade of events that includes recruitment of an additional factor, Cdc...

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Detalles Bibliográficos
Autores principales: Dueber, Erin C., Costa, Alessandro, Corn, Jacob E., Bell, Stephen D., Berger, James M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089459/
https://www.ncbi.nlm.nih.gov/pubmed/21227921
http://dx.doi.org/10.1093/nar/gkq1308