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Atomistic simulations reveal bubbles, kinks and wrinkles in supercoiled DNA

Although DNA is frequently bent and supercoiled in the cell, much of the available information on DNA structure at the atomistic level is restricted to short linear sequences. We report atomistic molecular dynamics (MD) simulations of a series of DNA minicircles containing between 65 and 110 bp whic...

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Detalles Bibliográficos
Autores principales: Mitchell, J. S., Laughton, C. A., Harris, Sarah A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089460/
https://www.ncbi.nlm.nih.gov/pubmed/21247872
http://dx.doi.org/10.1093/nar/gkq1312