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Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish

The nonsense-mediated mRNA decay (NMD) pathway is a highly conserved surveillance mechanism that is present in all eukaryotes. It prevents the synthesis of truncated proteins by selectively degrading mRNAs harbouring premature termination codons (PTCs). The core NMD effectors were originally identif...

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Detalles Bibliográficos
Autores principales: Anastasaki, Corina, Longman, Dasa, Capper, Amy, Patton, E. Elizabeth, Cáceres, Javier F.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089463/
https://www.ncbi.nlm.nih.gov/pubmed/21227923
http://dx.doi.org/10.1093/nar/gkq1319