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Tumour suppressor ING1b maintains genomic stability upon replication stress

The lesion bypass pathway, which is regulated by monoubiquitination of proliferating cell nuclear antigen (PCNA), is essential for resolving replication stalling due to DNA lesions. This process is important for preventing genomic instability and cancer development. Previously, it was shown that cel...

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Detalles Bibliográficos
Autores principales: Wong, Ronald P. C., Lin, Hanyang, Khosravi, Shahram, Piche, Brad, Jafarnejad, Seyed Mehdi, Chen, David W. C., Li, Gang
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089469/
https://www.ncbi.nlm.nih.gov/pubmed/21227930
http://dx.doi.org/10.1093/nar/gkq1337