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Tumour suppressor ING1b maintains genomic stability upon replication stress
The lesion bypass pathway, which is regulated by monoubiquitination of proliferating cell nuclear antigen (PCNA), is essential for resolving replication stalling due to DNA lesions. This process is important for preventing genomic instability and cancer development. Previously, it was shown that cel...
Autores principales: | Wong, Ronald P. C., Lin, Hanyang, Khosravi, Shahram, Piche, Brad, Jafarnejad, Seyed Mehdi, Chen, David W. C., Li, Gang |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089469/ https://www.ncbi.nlm.nih.gov/pubmed/21227930 http://dx.doi.org/10.1093/nar/gkq1337 |
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