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Identification of a novel epigenetic regulatory region within the pluripotency associated microRNA cluster, EEmiRC

The miR-290 cluster is expressed in embryonic stem cells (ESCs) and is important for the maintenance of pluripotency, but little is known about the mechanisms regulating the early embryonic microRNA cluster (EEmiRC) expression. Here we report the identification of a 332-bp intragenic enhancer (IE) a...

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Detalles Bibliográficos
Autores principales: Tata, Purushothama R., Tata, Nageswara R., Kühl, Michael, Sirbu, Ioan O.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089473/
https://www.ncbi.nlm.nih.gov/pubmed/21247880
http://dx.doi.org/10.1093/nar/gkq1344