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Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes

The stem cell protein Lin28 functions to inhibit the biogenesis of a group of miRNAs but also stimulates the expression of a subset of mRNAs at the post-transcriptional level, the underlying mechanism of which is not yet understood. Here we report the characterization of the molecular interplay betw...

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Detalles Bibliográficos
Autores principales: Jin, Jianyu, Jing, Wei, Lei, Xin-Xiang, Feng, Chen, Peng, Shuping, Boris-Lawrie, Kathleen, Huang, Yingqun
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089476/
https://www.ncbi.nlm.nih.gov/pubmed/21247876
http://dx.doi.org/10.1093/nar/gkq1350