AS160 Phosphotyrosine-binding Domain Constructs Inhibit Insulin-stimulated GLUT4 Vesicle Fusion with the Plasma Membrane

AS160 (TBC1D4) is a known Akt substrate that is phosphorylated downstream of insulin action and that leads to regulated traffic of GLUT4. As GLUT4 vesicle fusion with the plasma membrane is a highly regulated step in GLUT4 traffic, we investigated whether AS160 and 14-3-3 interactions are involved i...

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Detalles Bibliográficos
Autores principales: Koumanov, Françoise, Richardson, Judith D., Murrow, Beverley A., Holman, Geoffrey D.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Membrane Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089500/
https://www.ncbi.nlm.nih.gov/pubmed/21454690
http://dx.doi.org/10.1074/jbc.M111.226092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089500/
https://www.ncbi.nlm.nih.gov/pubmed/21454690
http://dx.doi.org/10.1074/jbc.M111.226092

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