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Temporal Profiling of Orexin Receptor-Arrestin-Ubiquitin Complexes Reveals Differences between Receptor Subtypes

Orexin G protein-coupled receptors (OxRs) and their cognate agonists have been implicated in a number of disorders since their recent discovery, ranging from narcolepsy to formation of addictive behavior. Bioluminescence resonance energy transfer assays of agonist-occupied OxRs provided evidence for...

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Detalles Bibliográficos
Autores principales: Dalrymple, Matthew B., Jaeger, Werner C., Eidne, Karin A., Pfleger, Kevin D. G.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089514/
https://www.ncbi.nlm.nih.gov/pubmed/21378163
http://dx.doi.org/10.1074/jbc.M111.223537