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Modification of Collagen by 3-Deoxyglucosone Alters Wound Healing through Differential Regulation of p38 MAP Kinase

BACKGROUND: Wound healing is a highly dynamic process that requires signaling from the extracellular matrix to the fibroblasts for migration and proliferation, and closure of the wound. This rate of wound closure is impaired in diabetes, which may be due to the increased levels of the precursor for...

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Detalles Bibliográficos
Autores principales: Loughlin, Danielle T., Artlett, Carol M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089600/
https://www.ncbi.nlm.nih.gov/pubmed/21573155
http://dx.doi.org/10.1371/journal.pone.0018676