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Timeless Links Replication Termination to Mitotic Kinase Activation

The mechanisms that coordinate the termination of DNA replication with progression through mitosis are not completely understood. The human Timeless protein (Tim) associates with S phase replication checkpoint proteins Claspin and Tipin, and plays an important role in maintaining replication fork st...

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Detalles Bibliográficos
Autores principales: Dheekollu, Jayaraju, Wiedmer, Andreas, Hayden, James, Speicher, David, Gotter, Anthony L., Yen, Tim, Lieberman, Paul M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089618/
https://www.ncbi.nlm.nih.gov/pubmed/21573113
http://dx.doi.org/10.1371/journal.pone.0019596