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Timeless Links Replication Termination to Mitotic Kinase Activation
The mechanisms that coordinate the termination of DNA replication with progression through mitosis are not completely understood. The human Timeless protein (Tim) associates with S phase replication checkpoint proteins Claspin and Tipin, and plays an important role in maintaining replication fork st...
Autores principales: | Dheekollu, Jayaraju, Wiedmer, Andreas, Hayden, James, Speicher, David, Gotter, Anthony L., Yen, Tim, Lieberman, Paul M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089618/ https://www.ncbi.nlm.nih.gov/pubmed/21573113 http://dx.doi.org/10.1371/journal.pone.0019596 |
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