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Specificity of Mimotope-Induced Anti-High Molecular Weight-Melanoma Associated Antigen (HMW-MAA) Antibodies Does Not Ensure Biological Activity

Vaccines based on peptide mimics (mimotopes) of conformational tumor antigen epitopes have been investigated for a variety of human tumors including breast cancer, tumors expressing the carcinoembryonic antigen, B cell lymphoma, neuroblastoma, and melanoma. In our previous work, we designed a vaccin...

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Detalles Bibliográficos
Autores principales: Latzka, Julia, Gaier, Sonja, Hofstetter, Gerlinde, Balazs, Nina, Smole, Ursula, Ferrone, Soldano, Scheiner, Otto, Breiteneder, Heimo, Pehamberger, Hubert, Wagner, Stefan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089623/
https://www.ncbi.nlm.nih.gov/pubmed/21573118
http://dx.doi.org/10.1371/journal.pone.0019383