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Functional Interactions between Retinoblastoma and c-MYC in a Mouse Model of Hepatocellular Carcinoma

Inactivation of the RB tumor suppressor and activation of the MYC family of oncogenes are frequent events in a large spectrum of human cancers. Loss of RB function and MYC activation are thought to control both overlapping and distinct cellular processes during cell cycle progression. However, how t...

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Detalles Bibliográficos
Autores principales: Saddic, Louis A., Wirt, Stacey, Vogel, Hannes, Felsher, Dean W., Sage, Julien
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089631/
https://www.ncbi.nlm.nih.gov/pubmed/21573126
http://dx.doi.org/10.1371/journal.pone.0019758