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A vital role for IL-2 trans-presentation in DC-mediated T cell activation in humans as revealed by daclizumab therapy
While previous studies have described CD25 expression on mature dendritic cells (mDCs) and their production of IL-2, it remains unclear how these molecules participate in the activation of T cells. In search of the mechanisms by which daclizumab, a humanized monoclonal antibody against CD25, inhibit...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089658/ https://www.ncbi.nlm.nih.gov/pubmed/21532597 http://dx.doi.org/10.1038/nm.2365 |