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Molecular modeling, organ culture and reverse genetics for a newly identified human rhinovirus C

A recently recognized human rhinovirus species C (HRV-C) is associated with up to half of HRV infections in young children. Here we propagated two HRV-C isolates ex vivo in organ culture of nasal epithelial cells, sequenced a new C15 isolate and developed the first, to our knowledge, reverse genetic...

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Detalles Bibliográficos
Autores principales: Bochkov, Yury A, Palmenberg, Ann C, Lee, Wai-Ming, Rathe, Jennifer A, Amineva, Svetlana P, Sun, Xin, Pasic, Thomas R, Jarjour, Nizar N, Liggett, Stephen B, Gern, James E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089712/
https://www.ncbi.nlm.nih.gov/pubmed/21483405
http://dx.doi.org/10.1038/nm.2358