The Styrene Metabolite, Phenylglyoxylic Acid, Induces Striatal-Motor Toxicity in the Rat: Influence of Dose Escalation/Reduction over Time

Exposure to the industrial solvent, styrene, induces locomotor and cognitive dysfunction in rats, and parkinsonian-like manifestations in man. The antipsychotic, haloperidol (HP), well known to induce striatal toxicity in man and animals, and styrene share a common metabolic pathway yielding p-fluor...

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Detalles Bibliográficos
Autores principales: Terre’Blanche, Gisella, Heyer, Nicolette, Bergh, Jacobus J., Mienie, Lodewyk J., van der Schyf, Cornelius J., Harvey, Brian H.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089729/
https://www.ncbi.nlm.nih.gov/pubmed/20931367
http://dx.doi.org/10.1007/s12640-010-9222-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089729/
https://www.ncbi.nlm.nih.gov/pubmed/20931367
http://dx.doi.org/10.1007/s12640-010-9222-y

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