Cargando…

The Styrene Metabolite, Phenylglyoxylic Acid, Induces Striatal-Motor Toxicity in the Rat: Influence of Dose Escalation/Reduction over Time

Exposure to the industrial solvent, styrene, induces locomotor and cognitive dysfunction in rats, and parkinsonian-like manifestations in man. The antipsychotic, haloperidol (HP), well known to induce striatal toxicity in man and animals, and styrene share a common metabolic pathway yielding p-fluor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Terre’Blanche, Gisella, Heyer, Nicolette, Bergh, Jacobus J., Mienie, Lodewyk J., van der Schyf, Cornelius J., Harvey, Brian H.
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2010
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089729/ https://www.ncbi.nlm.nih.gov/pubmed/20931367 http://dx.doi.org/10.1007/s12640-010-9222-y

Ejemplares similares

Treatment of an adrenomyeloneuropathy patient with Lorenzo's oil and supplementation with docosahexaenoic acid-A case report
por: Terre'Blanche, Gisella, et al.
Publicado: (2011)

Dual A(1) and A(2A) adenosine receptor antagonists, methoxy substituted 2-benzylidene-1-indanone, suppresses intestinal postprandial glucose and attenuates hyperglycaemia in fructose-streptozotocin diabetic rats
por: Sanni, Olakunle, et al.
Publicado: (2023)

C3 amino-substituted chalcone derivative with selective adenosine rA(1) receptor affinity in the micromolar range
por: Janse van Rensburg, Helena D., et al.
Publicado: (2020)

Design, synthesis and evaluation of amino-3,5-dicyanopyridines and thieno[2,3-b]pyridines as ligands of adenosine A(1) receptors for the potential treatment of epilepsy
por: Nkomba, Gaofenngwe, et al.
Publicado: (2022)

On the basis of sex: male vs. female rat adenosine A(1)/A(2A) receptor affinity
por: Janse van Rensburg, Helena D., et al.
Publicado: (2023)

Photogenerated Radical in Phenylglyoxylic Acid for in Vivo Hyperpolarized (13)C MR with Photosensitive Metabolic Substrates
por: Marco-Rius, Irene, et al.
Publicado: (2018)

Contribution towards a Metabolite Profile of the Detoxification of Benzoic Acid through Glycine Conjugation: An Intervention Study
por: Irwin, Cindy, et al.
Publicado: (2016)

The (1)H-NMR-based metabolite profile of acute alcohol consumption: A metabolomics intervention study
por: Irwin, Cindy, et al.
Publicado: (2018)

Effects of Styrene-metabolizing Enzyme Polymorphisms and Lifestyle Behaviors on Blood Styrene and Urinary Metabolite Levels in Workers Chronically Exposed to Styrene
por: Kim, Ki-Woong
Publicado: (2015)

Draft Genome Sequences of Potentially Pathogenic Clostridium perfringens Strains from Environmental Surface Water in the North West Province of South Africa
por: Fourie, Johannes Cornelius Jacobus, et al.
Publicado: (2019)

Synthesis of a New Molecularly Imprinted Polymer and Optimisation of Phenylglyoxylic Acid Extraction from Human Urine Samples Using a Central Composite Design within the Response Surface Methodology
por: Qronfla, Murad. M., et al.
Publicado: (2023)

Comparative Serum Fatty Acid Profiles of Captive and Free-Ranging Cheetahs (Acinonyx jubatus) in Namibia
por: Tordiffe, Adrian S. W., et al.
Publicado: (2016)

An Insight into the Growing Concerns of Styrene Monomer and Poly(Styrene) Fragment Migration into Food and Drink Simulants from Poly(Styrene) Packaging
por: Ajaj, Asmaa, et al.
Publicado: (2021)

A Morphological Study of Dynamically Vulcanized Styrene-Ethylene-Butylene-Styrene/Styrene-Butylene-Styrene/MethylVinylSilicon Rubber Thermoplastic Elastomer
por: Zhao, Chunxu, et al.
Publicado: (2022)

Downregulation of striatal Ca(V)1.3 inhibits the escalation of levodopa-induced dyskinesia in male and female parkinsonian rats of advanced age
por: Caulfield, Margaret E., et al.
Publicado: (2023)

Environmental Styrene Exposure and Sensory and Motor Function in Gulf Coast Residents
por: Werder, Emily J., et al.
Publicado: (2019)

Rutting Behaviour of Geopolymer and Styrene Butadiene Styrene-Modified Asphalt Binder
por: Hamid, Abdulrahman, et al.
Publicado: (2022)

Radiation Processing of Styrene-isoprene-styrene/Poly(ε-caprolactone) Blends
por: Lungulescu, Eduard-Marius, et al.
Publicado: (2022)

Alternating styrene–propylene and styrene–ethylene copolymers prepared by photocatalytic decarboxylation
por: Schué, Emmanuelle, et al.
Publicado: (2023)

Serum biomarkers of liver fibrosis identify changes in striatal metabolite levels
por: Zahr, Natalie, et al.
Publicado: (2023)

GC–MS-based urinary organic acid profiling reveals multiple dysregulated metabolic pathways following experimental acute alcohol consumption
por: Irwin, Cindy, et al.
Publicado: (2018)

Butadiene and Styrene Risks
Publicado: (1993)

Metabolism and toxicity of styrene.
por: Leibman, K C
Publicado: (1975)

Olefin–Styrene Copolymers
por: Galdi, Nunzia, et al.
Publicado: (2016)

Experimental Study of Tensile Properties of Styrene–Butadiene–Styrene Modified Asphalt Binders
por: Mieczkowski, Paweł, et al.
Publicado: (2021)

Aging Resistance of Silica Fume/Styrene-Butadiene-Styrene Composite-Modified Asphalt
por: Zhu, Jingrong, et al.
Publicado: (2021)

Study on Styrene-Butadiene-Styrene Modified Asphalt Binders Relaxation at Low Temperature
por: Dziadosz, Sylwia, et al.
Publicado: (2021)

Packaging Materials Based on Styrene-Isoprene-Styrene Triblock Copolymer Modified with Graphene
por: Zaharescu, Traian, et al.
Publicado: (2023)

The cross-tissue metabolic response of abalone (Haliotis midae) to functional hypoxia
por: Venter, Leonie, et al.
Publicado: (2018)

The use of poly(styrene-block-isobutylene-block-styrene) as a microshunt to treat glaucoma
por: Pinchuk, Leonard, et al.
Publicado: (2016)

The Effect of Direct-to-Plant Styrene-Butadiene-Styrene Block Copolymer Components on Bitumen Modification
por: Zhang, Wengang, et al.
Publicado: (2019)

Microstructure Development and Its Influence on the Properties of Styrene-Ethylene-Butylene-Styrene/Polystyrene Blends
por: Banerjee, Ritima, et al.
Publicado: (2018)

Influence of Ultraviolet Radiation Exposure Time on Styrene-Ethylene-Butadiene-Styrene (SEBS) Copolymer
por: Garcia-Garcia, Daniel, et al.
Publicado: (2020)

Evaluation of the Aging of Styrene-Butadiene-Styrene Modified Asphalt Binder with Different Polymer Additives
por: Wu, Bangwei, et al.
Publicado: (2021)

Asymmetric azidohydroxylation of styrene derivatives mediated by a biomimetic styrene monooxygenase enzymatic cascade
por: Martínez-Montero, Lía, et al.
Publicado: (2021)

Anion Exchange Membrane Based on Sulfonated Poly (Styrene-Ethylene-Butylene-Styrene) Copolymers
por: Park, Hye-Seon, et al.
Publicado: (2021)

Laboratory Evaluation of Asphalt Binders Containing Styrene-Butadiene-Styrene (SBS) and Processed Oil
por: Hemmati, Navid, et al.
Publicado: (2023)

A hypothetical astrocyte–microglia lactate shuttle derived from a (1)H NMR metabolomics analysis of cerebrospinal fluid from a cohort of South African children with tuberculous meningitis
por: Mason, Shayne, et al.
Publicado: (2014)

Clinical studies of styrene workers: initial findings.
por: Lorimer, W V, et al.
Publicado: (1976)

Addressing the barriers to implementing model based designs in dose escalation studies
por: Cornelius, Victoria, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_hmrtndu9qtdg5ovbeili6aqh9r