Specific Silencing of L392V PSEN1 Mutant Allele by RNA Interference

RNA interference (RNAi) technology provides a powerful molecular tool to reduce an expression of selected genes in eukaryotic cells. Short interfering RNAs (siRNAs) are the effector molecules that trigger RNAi. Here, we describe siRNAs that discriminate between the wild type and mutant (1174 C→G) al...

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Detalles Bibliográficos
Autores principales: Sierant, Malgorzata, Paduszynska, Alina, Kazmierczak-Baranska, Julia, Nacmias, Benedetta, Sorbi, Sandro, Bagnoli, Silvia, Sochacka, Elzbieta, Nawrot, Barbara
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090069/
https://www.ncbi.nlm.nih.gov/pubmed/21559198
http://dx.doi.org/10.4061/2011/809218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090069/
https://www.ncbi.nlm.nih.gov/pubmed/21559198
http://dx.doi.org/10.4061/2011/809218

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