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Rosiglitazone-Mediated Effects on Skeletal Muscle Gene Expression Correlate with Improvements in Insulin Sensitivity in Individuals with HIV-Insulin Resistance

Rosiglitazone, an agonist of peroxisome proliferator activated receptor (PPARγ), improves insulin sensitivity by increasing insulin-stimulated glucose uptake into muscle tissue. This study was undertaken to assess changes in expression of PPAR-regulated genes in muscle tissue following treatment of...

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Detalles Bibliográficos
Autores principales: Mynarcik, Dennis C., McNurlan, Margaret A., Melendez, Mark M., Vosswinkel, James A., Gelato, Marie C.
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090220/
https://www.ncbi.nlm.nih.gov/pubmed/21559208
http://dx.doi.org/10.4061/2011/736425