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Rosiglitazone-Mediated Effects on Skeletal Muscle Gene Expression Correlate with Improvements in Insulin Sensitivity in Individuals with HIV-Insulin Resistance
Rosiglitazone, an agonist of peroxisome proliferator activated receptor (PPARγ), improves insulin sensitivity by increasing insulin-stimulated glucose uptake into muscle tissue. This study was undertaken to assess changes in expression of PPAR-regulated genes in muscle tissue following treatment of...
Autores principales: | Mynarcik, Dennis C., McNurlan, Margaret A., Melendez, Mark M., Vosswinkel, James A., Gelato, Marie C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
SAGE-Hindawi Access to Research
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090220/ https://www.ncbi.nlm.nih.gov/pubmed/21559208 http://dx.doi.org/10.4061/2011/736425 |
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