(-)-Pentazocine induces visceral chemical antinociception, but not thermal, mechanical, or somatic chemical antinociception, in μ-opioid receptor knockout mice

BACKGROUND: (-)-Pentazocine has been hypothesized to induce analgesia via the κ-opioid (KOP) receptor, although the involvement of other opioid receptor subtypes in the effects of pentazocine remains unknown. In this study, we investigated the role of the μ-opioid (MOP) receptor in thermal, mechanic...

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Detalles Bibliográficos
Autores principales: Ide, Soichiro, Minami, Masabumi, Uhl, George R, Satoh, Masamichi, Sora, Ichiro, Ikeda, Kazutaka
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090351/
https://www.ncbi.nlm.nih.gov/pubmed/21477373
http://dx.doi.org/10.1186/1744-8069-7-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090351/
https://www.ncbi.nlm.nih.gov/pubmed/21477373
http://dx.doi.org/10.1186/1744-8069-7-23

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