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Piper sarmentosum inhibits ICAM-1 and Nox4 gene expression in oxidative stress-induced human umbilical vein endothelial cells

BACKGROUND: Aqueous extract of Piper sarmentosum (AEPS) is known to possess antioxidant and anti-atherosclerotic activities but the mechanism responsible for it remains unclear. In early part of atherosclerosis, nuclear factor-kappa B (NF-κB) induces the expression of cellular adhesion molecules suc...

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Detalles Bibliográficos
Autores principales: Ugusman, Azizah, Zakaria, Zaiton, Hui, Chua Kien, Megat Mohd Nordin, Nor Anita
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090383/
https://www.ncbi.nlm.nih.gov/pubmed/21496279
http://dx.doi.org/10.1186/1472-6882-11-31