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The Thermal Structural Transition of α-Crystallin Inhibits the Heat Induced Self-Aggregation

[Image: see text]-crystallin, the major constituent of human lens, is a member of the heat-shock proteins family and it is known to have a quaternary structural transition at [Image: see text]. The presence of calcium ions and/or temperature changes induce supramolecular self-aggregation, a process...

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Detalles Bibliográficos
Autores principales: Maulucci, Giuseppe, Papi, Massimiliano, Arcovito, Giuseppe, De Spirito, Marco
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090392/
https://www.ncbi.nlm.nih.gov/pubmed/21573059
http://dx.doi.org/10.1371/journal.pone.0018906