Cargando…

Crystal Structures of Two Aminoglycoside Kinases Bound with a Eukaryotic Protein Kinase Inhibitor

Antibiotic resistance is recognized as a growing healthcare problem. To address this issue, one strategy is to thwart the causal mechanism using an adjuvant in partner with the antibiotic. Aminoglycosides are a class of clinically important antibiotics used for the treatment of serious infections. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Fong, Desiree H., Xiong, Bing, Hwang, Jiyoung, Berghuis, Albert M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090406/
https://www.ncbi.nlm.nih.gov/pubmed/21573013
http://dx.doi.org/10.1371/journal.pone.0019589