Deep Sequencing Reveals Direct Targets of Gammaherpesvirus-Induced mRNA Decay and Suggests That Multiple Mechanisms Govern Cellular Transcript Escape

One characteristic of lytic infection with gammaherpesviruses, including Kaposi's sarcoma-associated herpesvirus (KSHV), Epstein-Barr virus (EBV) and murine herpesvirus 68 (MHV68), is the dramatic suppression of cellular gene expression in a process known as host shutoff. The alkaline exonuclea...

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Detalles Bibliográficos
Autores principales: Clyde, Karen, Glaunsinger, Britt A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090416/
https://www.ncbi.nlm.nih.gov/pubmed/21573023
http://dx.doi.org/10.1371/journal.pone.0019655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090416/
https://www.ncbi.nlm.nih.gov/pubmed/21573023
http://dx.doi.org/10.1371/journal.pone.0019655

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