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A comparison of scopolamine and biperiden as a rodent model for cholinergic cognitive impairment
RATIONALE: The nonselective muscarinic antagonist scopolamine hydrobromide (SCOP) is employed as the gold standard for inducing memory impairments in healthy humans and animals. However, its use remains controversial due to the wide spectrum of behavioral effects of this drug. OBJECTIVE: The present...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090581/ https://www.ncbi.nlm.nih.gov/pubmed/21336581 http://dx.doi.org/10.1007/s00213-011-2171-1 |