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Detection of EpCAM-Negative and Cytokeratin-Negative Circulating Tumor Cells in Peripheral Blood

Enrichment of rare circulating tumor cells (CTCs) in blood is typically achieved using antibodies to epithelial cell adhesion molecule (EpCAM), with detection using cytokeratin (CK) antibodies. However, EpCAM and CK are not expressed in some tumors and can be downregulated during epithelial-to-mesen...

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Detalles Bibliográficos
Autores principales: Mikolajczyk, Stephen D., Millar, Lisa S., Tsinberg, Pavel, Coutts, Stephen M., Zomorrodi, Maryam, Pham, Tam, Bischoff, Farideh Z., Pircher, Tony J.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090615/
https://www.ncbi.nlm.nih.gov/pubmed/21577258
http://dx.doi.org/10.1155/2011/252361