Mining the TRAF6/p62 interactome for a selective ubiquitination motif

A new approach is described here to predict ubiquitinated substrates of the E3 ubiquitin ligase, TRAF6, which takes into account its interaction with the scaffold protein SQSTM1/p62. A novel TRAF6 ubiquitination motif defined as [–(hydrophobic)–k–(hydrophobic)–x–x–(hydrophobic)– (polar)–(hydrophobic...

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Detalles Bibliográficos
Autores principales: Jadhav, Trafina S, Wooten, Marie W, Wooten, Michael C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090762/
https://www.ncbi.nlm.nih.gov/pubmed/21554762
http://dx.doi.org/10.1186/1753-6561-5-S2-S4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090762/
https://www.ncbi.nlm.nih.gov/pubmed/21554762
http://dx.doi.org/10.1186/1753-6561-5-S2-S4

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