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Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid-binding Globulins
The release of hormones from thyroxine-binding globulin (TBG) and corticosteroid-binding globulin (CBG) is regulated by movement of the reactive center loop in and out of the β-sheet A of the molecule. To investigate how these changes are transmitted to the hormone-binding site, we developed a sensi...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091225/ https://www.ncbi.nlm.nih.gov/pubmed/21325280 http://dx.doi.org/10.1074/jbc.M110.171082 |