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Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid-binding Globulins

The release of hormones from thyroxine-binding globulin (TBG) and corticosteroid-binding globulin (CBG) is regulated by movement of the reactive center loop in and out of the β-sheet A of the molecule. To investigate how these changes are transmitted to the hormone-binding site, we developed a sensi...

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Detalles Bibliográficos
Autores principales: Qi, Xiaoqiang, Loiseau, François, Chan, Wee Lee, Yan, Yahui, Wei, Zhenquan, Milroy, Lech-Gustav, Myers, Rebecca M., Ley, Steven V., Read, Randy J., Carrell, Robin W., Zhou, Aiwu
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091225/
https://www.ncbi.nlm.nih.gov/pubmed/21325280
http://dx.doi.org/10.1074/jbc.M110.171082