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DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines

BACKGROUND: DNA methylation is an essential epigenetic mechanism involved in gene regulation and disease, but little is known about the mechanisms underlying inter-individual variation in methylation profiles. Here we measured methylation levels at 22,290 CpG dinucleotides in lymphoblastoid cell lin...

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Detalles Bibliográficos
Autores principales: Bell, Jordana T, Pai, Athma A, Pickrell, Joseph K, Gaffney, Daniel J, Pique-Regi, Roger, Degner, Jacob F, Gilad, Yoav, Pritchard, Jonathan K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091299/
https://www.ncbi.nlm.nih.gov/pubmed/21251332
http://dx.doi.org/10.1186/gb-2011-12-1-r10