Cargando…

Network analysis of skin tumor progression identifies a rewired genetic architecture affecting inflammation and tumor susceptibility

BACKGROUND: Germline polymorphisms can influence gene expression networks in normal mammalian tissues and can affect disease susceptibility. We and others have shown that analysis of this genetic architecture can identify single genes and whole pathways that influence complex traits, including infla...

Descripción completa

Detalles Bibliográficos
Autores principales: Quigley, David A, To, Minh D, Kim, Il Jin, Lin, Kevin K, Albertson, Donna G, Sjolund, Jonas, Pérez-Losada, Jesús, Balmain, Allan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091303/
https://www.ncbi.nlm.nih.gov/pubmed/21244661
http://dx.doi.org/10.1186/gb-2011-12-1-r5