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Network analysis of skin tumor progression identifies a rewired genetic architecture affecting inflammation and tumor susceptibility
BACKGROUND: Germline polymorphisms can influence gene expression networks in normal mammalian tissues and can affect disease susceptibility. We and others have shown that analysis of this genetic architecture can identify single genes and whole pathways that influence complex traits, including infla...
Autores principales: | Quigley, David A, To, Minh D, Kim, Il Jin, Lin, Kevin K, Albertson, Donna G, Sjolund, Jonas, Pérez-Losada, Jesús, Balmain, Allan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091303/ https://www.ncbi.nlm.nih.gov/pubmed/21244661 http://dx.doi.org/10.1186/gb-2011-12-1-r5 |
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