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CTCF binding site classes exhibit distinct evolutionary, genomic, epigenomic and transcriptomic features
BACKGROUND: CTCF (CCCTC-binding factor) is an evolutionarily conserved zinc finger protein involved in diverse functions ranging from negative regulation of MYC, to chromatin insulation of the beta-globin gene cluster, to imprinting of the Igf2 locus. The 11 zinc fingers of CTCF are known to differe...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091324/ https://www.ncbi.nlm.nih.gov/pubmed/19922652 http://dx.doi.org/10.1186/gb-2009-10-11-r131 |