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CTCF binding site classes exhibit distinct evolutionary, genomic, epigenomic and transcriptomic features

BACKGROUND: CTCF (CCCTC-binding factor) is an evolutionarily conserved zinc finger protein involved in diverse functions ranging from negative regulation of MYC, to chromatin insulation of the beta-globin gene cluster, to imprinting of the Igf2 locus. The 11 zinc fingers of CTCF are known to differe...

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Detalles Bibliográficos
Autores principales: Essien, Kobby, Vigneau, Sebastien, Apreleva, Sofia, Singh, Larry N, Bartolomei, Marisa S, Hannenhalli, Sridhar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091324/
https://www.ncbi.nlm.nih.gov/pubmed/19922652
http://dx.doi.org/10.1186/gb-2009-10-11-r131