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The MUC1 Cytoplasmic Tail and Tandem Repeat Domains Contribute to Mammary Oncogenesis in FVB Mice

BACKGROUND: Though the importance of the transmembrane mucin MUC1 in mammary oncogenesis has long been recognized, the relative contributions of the cytoplasmic tail and tandem repeat domains are poorly understood. METHODS: To address this, mouse models of mammary carcinogenesis were created express...

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Detalles Bibliográficos
Autores principales: Hattrup, Christine L., Bradley, Judy M., Kotlarczyk, Kari L., Madsen, Cathy S., Hentz, Joseph G., Marler, Ronald J., Gendler, Sandra J.
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091404/
https://www.ncbi.nlm.nih.gov/pubmed/21655373