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Heading Down the Wrong Pathway: on the Influence of Correlation within Gene Sets

BACKGROUND: Analysis of microarray experiments often involves testing for the overrepresentation of pre-defined sets of genes among lists of genes deemed individually significant. Most popular gene set testing methods assume the independence of genes within each set, an assumption that is seriously...

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Detalles Bibliográficos
Autores principales: Gatti, Daniel M, Barry, William T, Nobel, Andrew B, Rusyn, Ivan, Wright, Fred A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091509/
https://www.ncbi.nlm.nih.gov/pubmed/20955544
http://dx.doi.org/10.1186/1471-2164-11-574