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Heading Down the Wrong Pathway: on the Influence of Correlation within Gene Sets
BACKGROUND: Analysis of microarray experiments often involves testing for the overrepresentation of pre-defined sets of genes among lists of genes deemed individually significant. Most popular gene set testing methods assume the independence of genes within each set, an assumption that is seriously...
Autores principales: | Gatti, Daniel M, Barry, William T, Nobel, Andrew B, Rusyn, Ivan, Wright, Fred A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091509/ https://www.ncbi.nlm.nih.gov/pubmed/20955544 http://dx.doi.org/10.1186/1471-2164-11-574 |
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