Is human blood a good surrogate for brain tissue in transcriptional studies?

BACKGROUND: Since human brain tissue is often unavailable for transcriptional profiling studies, blood expression data is frequently used as a substitute. The underlying hypothesis in such studies is that genes expressed in brain tissue leave a transcriptional footprint in blood. We tested this hypo...

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Detalles Bibliográficos
Autores principales: Cai, Chaochao, Langfelder, Peter, Fuller, Tova F, Oldham, Michael C, Luo, Rui, van den Berg, Leonard H, Ophoff, Roel A, Horvath, Steve
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091510/
https://www.ncbi.nlm.nih.gov/pubmed/20961428
http://dx.doi.org/10.1186/1471-2164-11-589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091510/
https://www.ncbi.nlm.nih.gov/pubmed/20961428
http://dx.doi.org/10.1186/1471-2164-11-589

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