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Ubiquitin over-expression phenotypes and ubiquitin gene molecular misreading during aging in Drosophila melanogaster

Molecular Misreading (MM) is the inaccurate conversion of genomic information into aberrant proteins. For example, when RNA polymerase II transcribes a GAGAG motif it synthesizes at low frequency RNA with a two-base deletion. If the deletion occurs in a coding region, translation will result in prod...

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Detalles Bibliográficos
Autores principales: Hoe, Nicholas, Huang, Chung M., Landis, Gary, Verhage, Marian, Ford, Daniel, Yang, Junsheng, van Leeuwen, Fred W., Tower, John
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091519/
https://www.ncbi.nlm.nih.gov/pubmed/21415465