RasGrf1 deficiency delays aging in mice

RasGRF1 is a Ras-guanine nucleotide exchange factor implicated in a variety of physiological processes including learning and memory and glucose homeostasis. To determine the role of RASGRF1 in aging, lifespan and metabolic parameters were analyzed in aged RasGrf1(−/−) mice. We observed that mice de...

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Detalles Bibliográficos
Autores principales: Borrás, Consuelo, Monleón, Daniel, López-Grueso, Raul, Gambini, Juan, Orlando, Leonardo, Pallardó, Federico V., Santos, Eugenio, Viña, José, Font de Mora, Jaime
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091520/
https://www.ncbi.nlm.nih.gov/pubmed/21422498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091520/
https://www.ncbi.nlm.nih.gov/pubmed/21422498

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