The Werner syndrome helicase protein is required for cell proliferation, immortalization, and tumorigenesis in Scaffold Attachment Factor B1 deficient mice

Werner syndrome (WS) is a rare disorder characterized by the premature onset of several pathologies associated with aging. The gene responsible for WS codes for a RecQ-type DNA helicase and is believed to be involved in different aspects of DNA repair, replication, and transcription. We recently ide...

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Detalles Bibliográficos
Autores principales: Lachapelle, Sophie, Oesterreich, Steffi, Lebel, Michel
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091521/
https://www.ncbi.nlm.nih.gov/pubmed/21464516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091521/
https://www.ncbi.nlm.nih.gov/pubmed/21464516

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