Regulation of life span by mitochondrial respiration: the HIF-1 and ROS connection

A mild reduction in mitochondrial respiration extends the life span of many species, including C. elegans. We recently showed that hypoxia-inducible factor 1 (HIF-1) is required for the acquisition of a long life span by mutants with reduced respiration in C. elegans. We suggested that increased lev...

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Detalles Bibliográficos
Autores principales: Hwang, Ara B., Lee, Seung-Jae
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091523/
https://www.ncbi.nlm.nih.gov/pubmed/21389351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091523/
https://www.ncbi.nlm.nih.gov/pubmed/21389351

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