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Regulation of life span by mitochondrial respiration: the HIF-1 and ROS connection
A mild reduction in mitochondrial respiration extends the life span of many species, including C. elegans. We recently showed that hypoxia-inducible factor 1 (HIF-1) is required for the acquisition of a long life span by mutants with reduced respiration in C. elegans. We suggested that increased lev...
Autores principales: | Hwang, Ara B., Lee, Seung-Jae |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091523/ https://www.ncbi.nlm.nih.gov/pubmed/21389351 |
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