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Brain transcriptional stability upon prion protein-encoding gene invalidation in zygotic or adult mouse

BACKGROUND: The physiological function of the prion protein remains largely elusive while its key role in prion infection has been expansively documented. To potentially assess this conundrum, we performed a comparative transcriptomic analysis of the brain of wild-type mice with that of transgenic m...

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Detalles Bibliográficos
Autores principales: Chadi, Sead, Young, Rachel, Le Guillou, Sandrine, Tilly, Gaëlle, Bitton, Frédérique, Martin-Magniette, Marie-Laure, Soubigou-Taconnat, Ludivine, Balzergue, Sandrine, Vilotte, Marthe, Peyre, Coralie, Passet, Bruno, Béringue, Vincent, Renou, Jean-Pierre, Le Provost, Fabienne, Laude, Hubert, Vilotte, Jean-Luc
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091645/
https://www.ncbi.nlm.nih.gov/pubmed/20649983
http://dx.doi.org/10.1186/1471-2164-11-448