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Toxicogenomic analysis of exposure to TCDD, PCB126 and PCB153: identification of genomic biomarkers of exposure to AhR ligands

BACKGROUND: Two year cancer bioassays conducted by the National Toxicology Program have shown chronic exposure to dioxin-like compounds (DLCs) to lead to the development of both neoplastic and non-neoplastic lesions in the hepatic tissue of female Sprague Dawley rats. Most, if not all, of the hepato...

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Detalles Bibliográficos
Autores principales: Ovando, Bladimir J, Ellison, Corie A, Vezina, Chad M, Olson, James R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091730/
https://www.ncbi.nlm.nih.gov/pubmed/20959002
http://dx.doi.org/10.1186/1471-2164-11-583